DMi8 S Inverted Microscope Solution

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Leica DMI8 S - Inverted Microscope
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Leica - DMi8 S Inverted Microscope Solution - กล้องจุลทรรศน์หัวกลับ รุ่น DMi8 S

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DMi8 S Inverted Microscope Solution

กล้องจุลทรรศน์หัวกลับ ยี่ห้อ ไลก้า รุ่น DMi8 S

กล้องจุลทรรศน์หัวกลับ ยี่ห้อ ไลก้ารุ่น DMi8 S ออกแบบมาเพื่อรองรับงานวิจัยทางด้าน live cell คุณสามารถติดตามพัฒนาการของเซลล์เดียวในจานเลี้ยงเซลล์ หรือการทำ single molecule resolution ก็สามารถทำได้ ซึ่งกล้องรุ่นนี้รองรับการใช้งานอย่างหลากหลาย โดย DMi8 S นี้จะช่วยให้คุณเห็นมากขึ้น เห็นได้รวดเร็วขึ้น และช่วยให้คุณสามารถค้นหาสิ่งที่ต้องการได้

  • เห็นมากขึ้น โดยเพิ่มพื้นที่การมองเห็นมากขึ้นถึง 10,000 เท่า
  • เห็นได้รวดเร็วขึ้น สามารถการทำการทดลองเร็วขึ้น 5 เท่า
  • เห็นในสิ่งที่ซ่อนอยู่ ในสิ่งที่ต้องการ

DMi8 S Inverted Microscope Solution

The modular DMi8 inverted microscope is the heart of the DMi8 S platform solution. For routine to live cell research, the DMi8 S platform is a complete solution. Whether you need to precisely follow the development of a single cell in a dish, screen through multiple assays, obtain single molecule resolution or tease out behaviors of complex processes, a DMi8 S system will enable you to see more, see faster, and find the hidden.

DMi8 S for advanced widefield research

Starting from discovery and analysis of single molecules and culminating in breakthroughs in understanding and treating human health, the key to the next scientific discovery lies in finding the missing links connecting your data.

The DMi8 S is a flexible solution for advanced widefield research. The new DMi8 S platform extends the flexibility of the DMi8 microscope, adding high-speed control, Infinity TIRF plus advanced software capabilities to create the solution for your advanced live cell imaging.

DMi8 S Platform Solutions

See more – Increase your viewing area up to 10,000x

Switch from searching image by image to seeing the full overview of your samples. Like a GPS for your cells, the software module LAS X Navigator ensures that you always have a clear roadmap to brilliant data.

Create fast overviews of your samples and identify the important details instantly. Then set up high resolution image acquisition automatically using templates for slides, dishes and multiwell plates.

Find your answers

No matter what experiments you have in mind, LAS X Navigator is the key to all applications on your DMi8 S platform.

  • Generate live overviews
  • Create spiral scans to search in the vicinity of your current location
  • Display images in sample carrier templates for quick orientation
  • Work flexibly with different magnifications, cameras, detectors, and contrasting methods in the same workspace
  • Define multiple regions and positions for high resolution scans or multiwell projects
  • Zoom swiftly in and out of your sample
  • Move to any stage location by mouse click
Zebrafish larvae. Courtesy of Ravindra Peravali, Institute of Toxicology and Genetics, Eggenstein-Leopoldshafen, Germany.
Zebrafish larvae. Courtesy of Ravindra Peravali, Institute of Toxicology and Genetics, Eggenstein-Leopoldshafen, Germany.

See faster – Experiments up to 5 x faster

The DMi8 S imaging solution powered by LAS X Synapse advanced sequencer eliminates the bottlenecks between system components, resulting in dramatically faster imaging. With an integrated real-time controller that directly interacts with all of your hardware components, cameras and peripherals, you can control your entire system with micro-second precision.

Combine high speed External Filter Wheels with multi-position stage experiments and benefit from filter wheels with high precision stage control.

Time lapse experiments up to 5x faster mean you can both save time and capture more details. No matter which of the instrument components are part of the experiment, the system will run at the highest speed possible. 

Faster imaging with DMi8 S. Comparison of total time for standard experiments before and after LAS X Synapse control.
Faster imaging with DMi8 S. Comparison of total time for standard experiments before and after LAS X Synapse control.

Precise control

For specialized live cell applications, you can now add additional devices to the system and set up high-speed experiments with trigger controled third party devices.

The DMi8 S platform is powered by LAS X Synapse advanced sequencer, which allows you to freely specify the behavior of connections and create fast imaging sequences to analyze an organism’s response to external stimuli delivered via third party devices.

Define both digital and analog signals, and set up the trigger signaling independently from the image acquisition with exact timings and full reproducibility.

The DMi8 S with LAS X Synapse allows you to achieve the highest acquisition speed possible by processing data more efficiently.

See the hidden – Activate, ablate, and bleach in one experiment

Add the Infinity TIRF to your DMi8 S platform to maximize the versatility of your system. You can perform Super Resolution, TIRF and several photomanipulation tasks within one time-lapse experiment using up to 5 lasers. 

Sensitive light applications like optogenetics or photoswitching can be performed alongside more demanding tasks like FRAP or ablation. Combine techniques even further using the fully automated, super-resolution capable Infinity TIRF to analyze membrane dynamics.

Comparison of traditional 16mm field of view (dotted line) versus 19mm field of view. Solenostemon scutellarioides leaf. Deconvolved autofluorescence. Image taken with a DFC9000 GT sCMOS camera on the DMi8 microscope.
Comparison of traditional 16mm field of view (dotted line) versus 19mm field of view. Solenostemon scutellarioides leaf. Deconvolved autofluorescence. Image taken with a DFC9000 GT sCMOS camera on the DMi8 microscope.

The DMi8 S is a versatile and userfriendly system that empowers biomedical researchers to probe molecular machineries within the cell with super-resolution, photo-manipulation and optogenetics.

Dr. Alessandro Esposito, Hutchison MRC Research Centre, University of Cambridge, UK

The DMi8 Microscope

Fully configurable with manual to motorized components, the DMi8 microscope allows you to build the imaging system for your research and budget needs. Flexibility is built-in, allowing you to add established options like DIC for unstained samples and Intelligent Automation. For time-lapse experiments use precise focus control with Adaptive Focus Control and Closed Loop Focus.

DMi8 S Platform Solutions